Evaluation of Phosphorylated Insulin like Growth Factor Binding Protein-1 and Sonographically Measured Cervical Length for Prediction of Preterm Birth in Threatened Preterm Labor: A Clinical Approach
نویسندگان
چکیده
Background and Objectives: Measurement of cervical length using Transvaginal Sonography (TVS) is commonly used to identify those patients of threatened preterm labor who are likely to deliver. Biochemical markers in cervical secretions namely fetal fibronectin and Phosphorylated Insulin like Growth Factor Binding Protien-1 (phIGFBP-1) have also been used to improve predictability. This study evaluated bedside kit test for phIGFBP-1 and cervical length measurement by TVS, individually and in combination, for prediction of preterm birth in patients with threatened preterm labor.
منابع مشابه
Fetal Fibronectin and Phosphorilated Insulin- like Growth Factor Binding Protein-1 as Predictors of Spontaneus Preterm Delivery
The aim of the paper was to assess the combined use of cervical length, fetal fibronectin and cervical phosphorylated insulin-like growth factor binding protein-1 (phIGFBP-1) in the prediction of preterm delivery in symptomatic women in the following 14 days. Cervical length was prospectively measured in 58 consecutive singleton pregnancies with intact membranes and regular contractions at 24–3...
متن کاملPhosphorylated insulin-like growth factor binding protein-1 and cervical measurement in women with threatening preterm birth.
OBJECTIVE To assess the efficacy of the cervical phosphorylated insulin-like growth factor binding protein-1 (pIGFBP-1) in combination with cervical length measurement for the prediction of preterm delivery. DESIGN Observational prospective study. SETTING University Hospital, Spain. SAMPLE A total of 276 women between 24 and 34 weeks gestational age complaining of uterine contractions and...
متن کاملControversies in diagnosis of preterm labour.
Despite scientific advances, efforts to prevent preterm birth can be disappointing. Obstetric care must focus on strategies to improve the outcome of preterm infants. The major goal is to delay preterm birth long enough to allow the transfer of women about to deliver preterm to a facility with a neonatal intensive care unit and to administer corticosteroids to enhance fetal lung maturation. A p...
متن کاملIs measurement of cervical length an accurate predictive tool in women with a history of preterm delivery who present with threatened preterm labor?
OBJECTIVE To determine whether sonographically measured cervical length is an effective predictive tool in women with threatened preterm labor and a history of past spontaneous preterm delivery. METHODS This was a retrospective cohort study of all women with singleton pregnancies who presented with preterm labor at less than 34 + 0 weeks' gestation and underwent sonographic measurement of cer...
متن کاملEvaluation of a bedside test for phosphorylated insulin-like growth factor binding protein-1 in preterm labour.
OBJECTIVE The objective of this study was to assess the efficacy of a bedside test kit for phosphorylated insulin-like growth factor binding protein-1 (IGFBP-1) in the diagnosis of preterm labour and the prediction of subsequent preterm delivery. MATERIALS AND METHODS We performed a bedside test for IGFBP-1 in 47 women who presented to the delivery suite in suspected preterm labour between 23...
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